Elovera Spf Ss 6k2g44

Elovera – SPF Lotion UV Spectrum Divided into following key regions: UV-C (270 to 290 nm). UV-B (290 to 320 nm). UV-A (320 to 400 nm). UV – A II (320 – 340 nm) UV – A I (340 – 400 nm) Sales Training

Elovera – SPF Lotion • • • •

Ratio of UV-A to UV-B is approximately 20:1. UV-A is constant throughout the year. UV-B is greatest during summer. UV-B & UV-A reach earth’s surface in amounts affected by altitude & season. • UV-C does not normally reach earths surface because of filtration by ozone & atmospheric moisture. • Atmosphere does not protect humans completely from damage by UV-B & UV-A

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Elovera – SPF Lotion • UV-B rays, have shorter wavelength Absorbed by superficial layers of skin, i.e. epidermis & cause visible damage. • UV-A rays have longer wavelength Penetrate deep into skin & cause invisible damage. UVA is a severe threat to skin health because of its carcinogenic effect. Damage can be immediate & long-term, with effects ranging from sunburn, rashes, cell & tissue damage to premature wrinkling. Sales Training

Elovera – SPF Lotion • Visible damage is reaction which is seen immediately after sun exposure e.g. immediate pigmentation, actinic erythema (sunburn), hyperkeratinisation & tanning. • Invisible damage of skin are those which cause damage to immune system, harms cell membranes, making it a favorite site for attack by free radicals. UV light can also destroy DNA & thereby cause cell death. Sales Training

Elovera – SPF Lotion • Sunscreens are sun protective lotions/ creams when applied to skin, absorbs UV radiation.

• Made of chemical absorbers, physical reflectors or mixture of both. • There are few chemicals that absorb both UV-A & UVB radiations. Hence combination sunscreens are formulated as they are enriched with both UV-A & UV-B absorbing chemicals to provide broad spectrum protection. Sales Training

Elovera – SPF Lotion • UV-A chemical sunscreen compounds include benzophenones (oxybenzone), avobenzone & mexoryl X. • UV-B chemical sunscreen compounds include para-aminobenzoic acid (PABA) & its derivatives, cinnamates, salicylates, octocrylene, ensilozole & camphor derivatives. Sales Training

Elovera – SPF Lotion Sun Protection Factor (SPF) • SPF is defined as the amount of UV radiation required to produce 1 minimal erythema dose (MED) on protected skin after application of 2 mg.cm² of sunscreen product divided by the amount of UV radiation required to produce 1 MED on unprotected skin. • MED (Minimal Erythema Dose) is the dose of radiation at a specific wavelength which will produce a delayed erythema response.

• SPF =

MED with Photoprotection --------------------------------MED without Photoprotection Sales Training

Elovera – SPF Lotion • It is recommended that broad-spectrum products with SPF of at least 15 be used. Broad-spectrum or fullspectrum sunscreen provides UV-B & UV-A protection.

• For children 6 months to 2 years, it is recommended to use sunscreen with SPF of at least 4, although 15 or higher is considered best. • Because baby’s bodies may not be developed enough to handle sunscreen chemicals, they should not be used on babies younger than 6 months of age. Sales Training

Elovera – SPF Lotion Criteria for an ideal sunscreen & how is Elovera – SPF closer to it? • High Sun Protection Factor: Therapeutic concentration of effective UV absorbing agents ensures effective protection. • Broad Spectrum Sunscreen: Both UVA & UVB absorbing sunactive agents have been included. • Protect against Visible & Invisible damages Sales Training

Elovera – SPF Lotion Criteria for an ideal sunscreen & how is Elovera – SPF closer to it? • Photo stability of formulation : After absorption of UV radiations sunscreen agents get converted into byproducts, which might prove allergic. Such allergic reactions are not reported with the sunactive agents in Elovera - SPF. All the ingredients are photostable. •

Waterproof : Sunscreen formulation with water proof property so that after application though patient might sweat but still the product will be retained on skin for longer time. Secondly sunscreens are widely prescribed to swimmers where they are exposed to more amount of reflected light so sun damages are common. Sales Training

Elovera – SPF Lotion Criteria for an ideal sunscreen & how is Elovera – SPF closer to it? •

Diffusion of Sunactive agents at dermis : The sunactive agents of Elovera - SPF are lipophilic so they easily diffuse at the level of dermis thus protecting from deeper penetrating UVA radiations.

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Non-Comedogenic : Sunscreens are often applied on face & are prescribed to teens, where acne is a concern. In such situations comedogenic formulation might worsen acne. Thus it is essential that product should be noncomedogenic. Elovera-SPF is noncomedogenic. Sales Training

Elovera – SPF Lotion Therapeutic applications of sunscreens Apart from photoprotection to normal skin sunscreens can also be applied in the following conditions to prevent further damage & improve condition of the skin. • Photocarcinogenesis Skin cancer because of excessive exposure to UV radiation. DNA can absorb UV radiation directly leading to characteristic mutations that apparently result in altered DNA quality control. Sales Training

Elovera – SPF Lotion Therapeutic applications of sunscreens Photoaging Skin aging because of excessive exposure to UV radiation. • Photoallergy Involves interaction of immune system & solar radiation resulting in damage to skin. Sales Training

Sunlight – Tissue Interaction UV Radiation (Photons)

DNA NADH, NADPH, Tryptophan, Riboflavin,Melanin (Chromophores*)

Release ROS

Oxidation of Lipids & Proteins Affect DNA repair

Dyspigmentation Photoaging Carcinogenesis NADH-Nicotinamide Adenine Dinucleotide,NADPH- Nicotinamide Adenine Dinucleotide Phosphate, * Atomic grouping on which colour depends. Sales Training

Elovera – SPF Lotion Therapeutic applications of sunscreens • Polymorphous light eruption (PMLE) Idiopathic skin eruption that occurs in susceptible individuals on exposure to UV radiation that is more intense than usual. Seen most commonly at the beginning of summer. • Porphyrias Caused by an inherited or acquired abnormality in the heme metabolic pathway. • Solar urticaria It is a rare rapidly developing reaction to UV exposure. Sales Training

Elovera – SPF Lotion Therapeutic applications of sunscreens

• Xeroderma pigmentosum Stems from a genetic defect in the ability to repair DNA. Skin neoplasms, including malignant melanoma as well as basal cell & squamous cell carcinoma. Sales Training

Elovera – SPF Lotion Therapeutic applications of sunscreens • Drug photosensitivity skin reactions Photosensitivity can occur in any individual exposed to photosensitive agents. Many anticancer drugs, antidepressants, antihistamines, antifungals, doxycycline, tetracycline, antiparasitic drugs, psoralens can cause photosensitivity. Sales Training

Elovera – SPF Lotion: Composition & Role of Ingredients • VITAMIN E ACETATE 0.5 % : Antioxidant & Photoprotection • ALOE EXTRACT 10 % : Protects morphology & number of Langerhans cells, Photoprotection, Reduces production of ILs. • AVOBENZONE 3 % : Photoprotection against UVA I • OXYBENZONE 3 % : Photoprotection against UVA II & UVB Boosts SPF value in combination with other UV B absorbers • OCTYL METHOXYCINNAMATE 7.5 % : Photoprotection against UV B CREAM BASE Sales Training

Elovera – SPF Lotion •

Mode of application Sufficient quantity should be applied to exposed areas 20 to 30 minutes before exposure to sunlight.

• AVAILABILITY 60 ML FLIP-TOP PLASTIC BOTTLE IN A CARTON. Sales Training

Elovera - SPF : Competition • Shade (Fulford) : OCTYL METHOXYCINNAMATE 7.5 % OXYBENZONE 3 % & AVOBENZONE 3 %. • Sunset (Merck) : OCTYL METHOXYCINNAMATE 7.5 % & OXYBENZONE 3 % • Spectraban (Stifel) • Sunban (H & H) • Umrella (Le Sante)

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Elovera - SPF : Competition • Suncross lotion (Ranbaxy) : OCTINOXATE 7.5 % OXYBENZONE 3 %, AVOBENZONE 2 % ZINC OXIDE 2 %. SPF-26, 100 ml- Rs.219/30 • Sunban Forte cream (H & H) : OCTYL METHOXYCINNAMATE 8.5 % OXYBENZONE 3 % Titanium Dioxide 6 % (In micronised silica coated) UVA/ UVB ratio 0.51 CWL 370 nm SPF-50, 60 gm- Rs.274/95 Sales Training