Pathophysiology- Pleural Effusion 15o3v
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PATHOPHSIOLOGY OF MALIGNANT PLEURAL EFFUSION Predisposing Factors: Age – Late Adulthood Lifestyle – Smoker for 20 years “3 sticks/day”
Precipitating Factor: HISTORY OF BREAST CANCER CANCER CELLS METASTIZ E
Enters lymphatic system
Enters bloodstream
Settles @ parietal lymphatic vessel of pleura
Travels along internal mammary arteries that branches to parietal circulatory system of pleura and settles in CANCER CELLS ACCUMULAT E AND PROLIFERAT E
Occlusion of stoma on the parietal pleura increases oncotic pressure
↑ capillary permeability or vascular disruption
MALIGNANT PLEURAL EFFUSION
Precipitating Factor: HISTORY OF BREAST CANCER CANCER CELLS METASTIZ E
Enters lymphatic system
Enters bloodstream
Settles @ parietal lymphatic vessel of pleura
Travels along internal mammary arteries that branches to parietal circulatory system of pleura and settles in CANCER CELLS ACCUMULAT E AND PROLIFERAT E
Occlusion of stoma on the parietal pleura increases oncotic pressure
↑ capillary permeability or vascular disruption
MALIGNANT PLEURAL EFFUSION
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