Chapter 20: The Muscular System
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Learning Objectives • Compare the location and function of smooth, cardiac, and skeletal muscle. • Describe the typical structure of a skeletal muscle.
• Briefly describe the mechanism of muscle contraction. • Explain how muscles work together to produce movement. • Describe the main types of movements produced by muscles.
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Learning Objectives (cont’d) • List some of the criteria for naming muscles and give examples of each. • Identify and use the roots pertaining to the muscular system. • Describe at least seven disorders that affect muscles. • Interpret abbreviations pertaining to muscles.
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Pretest 1. The neuromuscular junction is between a muscle and a: (a) gland (b) neuron
(c) bone (d) gonad
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Pretest 1. The neuromuscular junction is between a muscle and a : (a) gland (b) neuron
(c) bone (d) gonad
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Pretest 2. In the muscular system, the opposite of the origin is the: (a) counterorigin
(b) agonist (c) diaphragm (d) insertion
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Pretest 2. In the muscular system, the opposite of the origin is the: (a) counterorigin
(b) agonist (c) diaphragm (d) insertion
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Pretest 3. The quadriceps femoris muscle forms the anterior part of the: (a) neck
(b) back (c) thigh (d) abdomen
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Pretest 3. The quadriceps femoris muscle forms the anterior part of the: (a) neck
(b) back (c) thigh (d) abdomen
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Pretest 4. The opposite of flexion is: (a) rotation (b) antiflexion (c) relaxation (d) extension
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Pretest 4. The opposite of flexion is: (a) rotation (b) antiflexion (c) relaxation (d) extension
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Pretest 5. The opposite of abduction is: (a) adduction (b) circumduction (c) periduction (d) pronation
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Pretest 5. The opposite of abduction is: (a) adduction (b) circumduction (c) periduction (d) pronation
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Pretest 6. The band of connective tissue that attaches a muscle to a bone is a: (a) cartilage
(b) bursa (c) tendon (d) diaphysis
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Pretest 6. The band of connective tissue that attaches a muscle to a bone is a: (a) cartilage
(b) bursa (c) tendon (d) diaphysis
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Pretest 7. Polymyositis is inflammation of many: (a) sense organs (b) muscles (c) glands (d) bones
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Pretest 7. Polymyositis is inflammation of many: (a) sense organs (b) muscles (c) glands (d) bones
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Pretest 8. The word kinesis means: (a) movement (b) bending (c) stretching (d) pain
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Pretest 8. The word kinesis means: (a) movement (b) bending (c) stretching (d) pain
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Roots Pertaining to Muscles
Root
Meaning
Example
Definition of Example
my/o
muscle
myositis*
inflammation of muscle
muscul/o
muscle
musculature
muscle arrangement in a part or the whole body
in/o
fiber
inotropic
acting on (muscle) fibers
fasci/o
fascia
fasciodesis
binding (suture) of a fascia to a tendon or other fascia
* Note addition of s to this root before the suffix –itis.
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Roots Pertaining to Muscles (cont’d)
Root
Meaning
Example
Definition of Example
ten/o, tendin/o tendon
tenostosis
ossification of a tendon
ton/o
tone
cardiotonic
having a strengthening action on the heart
erg/o
work
ergonomics
study of the efficient use of energy during work
kin/o-, kine, kinesi/o, kinet/o
movement
kinesis
movement (adjective: kinetic)
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Types of Muscles • Smooth – Walls of hollow organs and ducts – Operates involuntarily
– Responsible for peristalsis • Cardiac – Myocardium of heart wall – Functions involuntarily – Responsible for pumping of heart Copyright © 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins
Types of Muscles (cont’d) • Skeletal – Attaches to bones – Responsible for voluntary movement – Maintains posture – Generates large portion of body heat
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Muscle Structure • Fibers held together in fascicles • Fascia covers muscle • Tendons attach muscles to bones
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Muscle Action • Skeletal muscles stimulated by motor neurons of nervous system • Acetylcholine released
– Prompts contraction • Requires actin and myosin to interact • ATP and calcium needed for this response • Partial contraction = tonus
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Muscle Action (cont’d) • Muscles work in pairs at ts to produce movement – Agonist = contraction – Antagonist = relaxation • Point of origin = muscle attachment point to stable part of skeleton • Point of insertion = muscle attachment point to moving part of skeleton
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Neuromuscular Junction
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Origins and Insertions
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Naming of Muscles • Named by: – Location – Direction of fibers – Size – Shape – Number of attachment heads • Indicated by suffix -ceps
– Its action • Indicated by suffix -or Copyright © 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins
Superficial Muscles, Anterior
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Superficial Muscles, Posterior
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Key Normal Structure and Function Term
Meaning
acetylcholine (ACh)
A neurotransmitter that stimulates contraction of skeletal muscles
actin
One of the two contractile proteins in muscle cells; the other is myosin
agonist
The muscle that carries out a given movement; prime mover
antagonist
The muscle that opposes an agonist (prime mover); it must relax when the agonist contracts
cardiac muscle
Involuntary muscle that makes up the wall of the heart
fascia
The fibrous sheath of connective tissue that covers a muscle; called deep fascia to differentiate it from the superficial fascia that underlies the skin (root: fasci/o); plural: fasciae
fascicle
A small bundle, as of muscle or nerve fibers
insertion
In a given movement, the point where a muscle is attached to a moving part of the skeleton
muscle
An organ that produces movement by contracting; also the tissue that composes such organs (root: my/o, muscul/o) Copyright © 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins
Key Normal Structure and Function (cont’d) Term
Meaning
myosin
One of the two contractile proteins in muscle cells; the other is actin
neuromuscular junction (NMJ)
The point of , or synapse, between a branch of a motor neuron and a muscle cell
origin
In a given movement, the point where a muscle is attached to a stable part of the skeleton
skeletal muscle
Voluntary muscle that moves the skeleton and maintains posture
smooth muscle
Involuntary muscle that makes up the wall of the hollow organs, vessels, and ducts; visceral muscle
synergist
A muscle that assists an agonist to produce a given movement
tendon
A fibrous band of connective tissue that attaches a muscle to a bone (root: ten/o, tendin/o)
tonus
A state of steady, partial contraction of muscle that maintains firmness; muscle tone (root: ton/o) Copyright © 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins
Clinical Aspects of the Muscular System • Myopathy is a disorder of the muscles • Techniques for diagnosing: – Study of muscle in action – Electromyography (EMG) – Serum assay of enzymes released in damaged muscles • Creatine kinase
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Muscular Dystrophy • Group of hereditary diseases – Most common is Duchenne muscular dystrophy
• Progressive, noninflammatory degeneration of muscles • Muscle tissue weakens and wastes away – Gradually replaced with connective tissue and fat
• May co-exist with: – Cardiomyopathy (disease of cardiac muscle) – Mental impairment Copyright © 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins
Polymyositis • Inflammation of skeletal muscle leading to weakness – Dysphagia – Cardiac problems • Cause unknown – May be related to viral infection or autoimmunity • Often associated with other systemic diseases – Rheumatoid arthritis – Lupus erythematosus
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Polymyositis (cont’d) • If skin is involved it is known as dermatomyositis • Symptoms – Erythema – Dermatitis – Lilac-colored rash • Diagnosis – Enzyme studies – EMG – Muscle biopsy
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Fibromyalgia Syndrome Often associated with: • Widespread muscle aches
• Tenderness • Stiffness • Fatigue
• Sleep disorders • Difficult to diagnose • Treatment –
Exercise program
–
Pain relievers, muscle relaxants, antidepressants Copyright © 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins
Chronic Fatigue Syndrome • Persistent fatigue of no known cause • Associated with:
–
Impaired memory
–
Sore throat
–
Painful lymph nodes
–
Muscle and t pain
–
Headaches
–
Sleep problems
–
Immune disorders
• Often occurs after viral infection • No consistent successful treatments Copyright © 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins
Myasthenia Gravis • Acquired autoimmune disease – Antibodies interfere with muscle stimulation at neuromuscular junction
– Progressive loss of muscle power • Especially in: • External eye muscles • Other facial muscles
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Amyotrophic Lateral Sclerosis • Lou Gehrig disease • Progressive degeneration of motor neurons, leads to muscular atrophy
• Signs: – Weakness – Cramping – Muscle twitching • Eventually leads to death Copyright © 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins
Stress Injuries • Include: –
Accidental injuries
–
Damage caused by overexertion or repetitive motion (RSI)
• Damage to soft tissue: –
Muscle strain
–
Inflammation
–
Tearing of ligaments and tendons
–
Bursitis
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Stress Injuries (cont’d) • Tendonitis is an inflammation of tendon, tendon sheath, and synovial membrane at t • Signs: pain, fatigue, weakness, stiffness, numbness, range of motion (ROM) • Treatment: rest, elevation, ice packs, bracing, medications – If more severe: steroid injections, ultrasound for deep heat, strength exercises, surgery, PT
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Common Upper Extremity Conditions
• Rotator cuff • Epicondylitis • Carpal tunnel syndrome • Trigger finger
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Carpal Tunnel Syndrome
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Common Lower Extremity Conditions
• Hamstring strain • Shin splint • Achilles tendonitis
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Key Disorders Term
Meaning
amyotrophic lateral sclerosis (ALS)
A disease caused by degeneration of motor neurons resulting in muscular weakness and atrophy; Lou Gehrig disease
chronic fatigue syndrome (CFS)
A disease of unknown cause that involves persistent fatigue, along with muscle and t pain and other symptoms; may be virally induced
dermatomyositis
A disease of unknown origin involving inflammation of muscles as well as dermatitis and skin rashes
fibromyalgia syndrome (FMS)
A disorder associated with widespread muscular aches and stiffness and having no known cause
muscular dystrophy
A group of hereditary muscular disorders marked by progressive weakness and atrophy of muscles
myasthenia gravis (MG)
A disease characterized by progressive muscular weakness; an autoimmune disease affecting the neuromuscular junction
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Key Disorders (cont’d) Term
Meaning
polymyositis
A disease of unknown cause involving muscle inflammation and weakness
repetitive strain injury
Tissue damage caused by repeated motion, usually overuse of the arm or hand in occupational activities such as writing, typing, painting, or using hand tools; also called repetitive motion injury, cumulative trauma injury, overuse syndrome
sprain
Injury to a ligament caused by abnormal or excessive force at a t, but without bone dislocation or fracture
strain
Trauma to a muscle because of overuse or excessive stretch; if severe, may involve tearing of muscle, bleeding, or separation of muscle from its tendon or separation of a tendon from bone
tendinitis
Inflammation of a tendon, usually caused by injury or overuse; the shoulder, elbow, and hip are common sites; also spelled tendonitis
tenosynovitis
Inflammation of a tendon sheath Copyright © 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins
Key Diagnosis
Term
Meaning
creatine kinase (CK)
An enzyme found in muscle tissue; the serum level of CK increases in cases of muscle damage; creatine phosphokinase (K)
electromyography (EMG)
Study of the electrical activity of muscles during contraction
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Supplementary Normal Structure and Function Term
Meaning
aponeurosis
A flat, white, sheetlike tendon that connects a muscle with the part that it moves
creatine
A substance in muscle cells that stores energy for contraction
glycogen
A complex sugar that is stored for energy in muscles and in the liver
isometric
Pertaining to a muscle action in which the muscle tenses but does not shorten (literally: same measurement)
isotonic
Pertaining to a muscle action in which the muscle shortens to accomplish movement (literally: same tone)
kinesthesia
Awareness of movement; perception of the weight, direction, and degree of movement (-esthesia means “sensation”)
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Supplementary Normal Structure and Function (cont’d) Term
Meaning
lactic acid
An acid produced in muscle cells that accumulates in muscle cells functioning without enough oxygen (anaerobically), as in times of great physical exertion
motor unit
A single motor neuron and all of the muscle cells that its branches stimulate
myoglobin
A pigment similar to hemoglobin that stores oxygen in muscle cells
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Supplementary Symptoms and Conditions Term
Meaning
asterixis
Rapid, jerky movements, especially in the hands, caused by intermittent loss of muscle tone
asthenia
Weakness (prefix a- meaning “without” with root sthen/o meaning “strength”)
ataxia
Lack of muscle coordination (from root tax/o meaning “order, arrangement”); adjective: ataxic
athetosis
A condition marked by slow, irregular, twisting movements, especially in the hands and fingers; adjective: athetotic
atrophy
A wasting away; a decrease in the size of a tissue or organ, such as the wasting of muscle from disuse
avulsion
Forcible tearing away of a part
clonus
Alternating spasmodic contraction and relaxation in a muscle; adjective: clonic
contracture
Permanent contraction of a muscle Copyright © 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins
Supplementary Symptoms and Conditions (cont’d) Term
Meaning
fasciculation
Involuntary small contractions or twitching of muscle fiber groups (fasciculi)
fibromyositis
A nonspecific term for pain, tenderness, and stiffness in muscles and ts
fibrositis
Inflammation of fibrous connective tissue, especially the muscle fasciae; marked by pain and stiffness
restless legs syndrome (RLS)
Uneasiness, twitching, or restlessness in the legs that occurs after going to bed and often leading to insomnia; may be caused by poor circulation or drug side effects
rhabdomyolysis
An acute disease involving diffuse destruction of skeletal muscle cells (root rhabd/o means “rod,” referring to the long, rodlike muscle cells)
rhabdomyoma
A benign tumor of skeletal muscle
rhabdomyosarcoma
A highly malignant tumor of skeletal muscle Copyright © 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins
Supplementary Symptoms and Conditions (cont’d) Term
Meaning
rheumatism
A general term for inflammation, soreness, and stiffness of muscles associated with pain in ts (adjective: rheumatic, rheumatoid)
spasm
A sudden, involuntary muscle contraction; may be clonic (contraction alternating with relaxation) or tonic (sustained); a strong and painful spasm may be called a cramp (adjectives, spastic, spasmodic)
spasticity
Increased tone or contractions of muscles causing stiff and awkward movements
tetanus
An acute infectious disease caused by the anaerobic bacillus Clostridium tetani. It is marked by persistent painful spasms of voluntary muscles; lockjaw
tetany
A condition marked by spasms, cramps, and muscle twitching caused by a metabolic imbalance, such as low blood calcium caused by underactivity of the parathyroid glands
torticollis
Spasmodic contraction of the neck muscles causing stiffness and twisting of the neck; wryneck Copyright © 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins
Supplementary Diagnosis and Treatment Term
Meaning
Chvostek sign
Spasm of facial muscles after a tap over the facial nerve; evidence of tetany
occupational therapy
Health profession concerned with increasing function and preventing disability through work and play activities. The goal of occupational therapy is to increase the patient's independence and quality of daily life
physical therapy
Health profession concerned with physical rehabilitation and prevention of disability. Exercise, massage, and other therapeutic methods are used to restore proper movement
rheumatology
The study and treatment of rheumatic diseases
Trousseau sign
Spasmodic contractions caused by pressing the nerve supplying a muscle; seen in tetany
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Supplementary Drugs Term
Meaning
antiinflammatory agent
Drug that reduces inflammation; includes steroids, such as cortisone, and nonsteroidal antiinflammatory drugs
COX-2 inhibitor
Nonsteroidal antiinflammatory drug that does not cause the stomach problems associated with other NSAIDs. Inhibits the cyclooxygenase (COX)-2 enzyme without affecting the COX-1 enzyme, a lack of which can cause stomach ulcers. Some of these drugs have been withdrawn from the market because of cardiac risk. Example is celecoxib (Celebrex)
muscle relaxant
A drug that reduces muscle tension; different forms may be used to relax muscles during surgery, to control spasticity, or to relieve musculoskeletal pain
nonsteroidal antiinflammatory drug (NSAID)
Drug that reduces inflammation but is not a steroid; examples include aspirin, ibuprofen, naproxen, and other inhibitors of prostaglandins, naturally produced substances that promote inflammation
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Abbreviations Ach
Acetylcholine
ALS
Amyotrophic lateral sclerosis
CFS
Chronic fatigue syndrome
C(P)K
Creatine (phospho)kinase
CTS
Carpal tunnel syndrome
EMG
Electromyography, electromyogram
FMS
Fibromyalgia syndrome
MG
Myasthenia gravis
MMT
Manual muscle test(ing)
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Abbreviations (cont’d) NMJ
Neuromuscular junction
OT
Occupational therapy/therapist
PT
Physical therapy/therapist
RICE
Rest, ice, compression, elevation
RLS
Restless legs syndrome
ROM
Range of motion
RSI
Repetitive strain injury
RTC
Rotator cuff
SITS
Supraspinatus, infraspinatus, teres minor, subscapularis (muscles)
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Post Test Underline the term that best fits the definition: 1. Movement away from the midline of the body: (abduction, adduction)
2. Fibrous band of connective tissue that connects muscle to bone: (tendon, fascia) 3. Muscle that carries out a given movement: (antagonist, agonist)
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Post Test Underline the term that best fits the definition: 1. Movement away from the midline of the body: (abduction, adduction)
2. Fibrous band of connective tissue that connects muscle to bone: (tendon, fascia) 3. Muscle that carries out a given movement or a prime mover: (antagonist, agonist)
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Post Test Fill in the blank with the best term. 4. ____________ is an acquired autoimmune disease in which antibodies interfere with muscle stimulation at the NMJ. 5. Injury to a ligament caused by abnormal or excessive force at a t, but without bone dislocation or fracture is known as a(n) ____________.
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Post Test Fill in the blank with the best term. 4. Myasthenia gravis is an acquired autoimmune disease in which antibodies interfere with muscle stimulation at the NMJ. 5. Injury to a ligament caused by abnormal or excessive force at a t, but without bone dislocation or fracture is known as a(n) sprain.
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