Guillain-Barre syndrome (GBS) By : SST Guillain-Barre syndrome (GBS) is an inflammatory disorder of the peripheral nerves & Cranial nerves. GBS is characterized by weakness and numbness or tingling in the legs and arms, and possible loss of movement and feeling in the legs, arms, upper body, and face.
Incidence
Guillain-Barre syndrome is a rare disorder; its frequency is about 1 to 2 cases in every 100,000 people per year .Men and women, young and old, are equally prone to contracting GBS.
GBS Causes Guillain-Barre
syndrome may autoimmune
be an disorder . Destruction of the myelin sheath the fatty substance that surrounds axons.
GBS Causes Guillain-Barre syndrome is not hereditary or contagious. Campylobacteriosis (usually from eating undercooked poultry) Flu (influenza), common cold Gastrointestinal viral infection HIV, Viral hepatitis A small number of cases have been known to occur after a medical procedure, such as minor surgery. Idiopathic
GBS Signs and Symptoms The first symptoms of GBS are usually numbness or tingling (paresthesia) in the toes and fingers, with progressive weakness in the arms and legs over the next few days. Some patients experience paresthesia only in their toes and legs; others only experience symptoms on one side of the body. The symptoms may stay in this phase, causing only mild difficulty in walking, requiring crutches or a walking stick.
GBS Signs and Symptoms Ascending or descending paralysis However, sometimes the illness progresses, leading to complete paralysis of the arms and legs. About one quarter of the time, the paralysis continues up the chest and freezes the breathing muscles, leaving the patient dependent on a ventilator. If the swallowing muscles are also affected, a feeding tube may be needed.
GBS Diagnosis Symptoms vary and its cause is unknown, GBS can be difficult to diagnose.If the symptoms occur uniformly across the body and progress rapidly, the diagnosis is easier. Observation of the patient's symptoms and an evaluation of the medical history provide the basis for diagnosis of Guillain-Barre syndrome, although no single observation is
3 Test that Can Confirm GBS Lumbar
puncture An elevated level of protein without an increase in the number of white blood cells (WBCs) in the fluid is characteristic of GBS. Electromyogram (EMG Nerve conduction velocity (NCV
Treatment GBS is considered a medical emergency – mgt in ICU. GBS can improve spontaneously, there are a number of treatments that facilitate recovery. Symptomatic & ive Monitor respiratory status Prevent complications of immobility
Other treatments : Plasmapharesis Immunogloulin Analgesics Muscle relaxant Anticonvulsants Cortocosteroids – NO Physical therapy – ive to active, assistive divices Hydrotherapy Counselling
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PROGNOSIS ??
EXERCISE!!!!! WHY
DO WE NEED TO PRIORITiZE A PATIENT WITH GBS ?
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